This study is based on data from the CPRD obtained under licence from the UK Medicines and Healthcare products Regulatory Agency
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X.WangH.ChenQ.et al (2017)
Binding of GLP-1 to GLP1R has multiple effects, including enhancing insulin secretion from pancreatic beta cells in response to glucose, increasing insulin expression, preventing beta-cell apoptosis, promoting the formation of new beta cells, reducing glucagon secretion, slowing down stomach emptying, promoting satiety, and improving glucose disposal in peripheral tissues
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doi: 10.1111/j.1600-079x.2008.00628.x 16 KrsmanoviLZStojilkoviSSMerelliFDufourSVirmaniACattKJ